Translational Surgery

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 2  |  Issue : 3  |  Page : 62--65

The role of ischemia-modified albumin levels in the diagnosis of acute appendicitis


Ersin Turan1, Baris Sevinç2, Hüseyin Kurku3, Gürcan Simsek4, Recep Demirgül4, Ömer Karahan2 
1 Department of General Surgery, Beyhekim State Hospital, Konya, Turkey
2 Department of General Surgery, Usak University Medical School, Usak, Turkey
3 Department of Biochemistry, Konya Training and Research Hospital, Konya, Turkey
4 Department of General Surgery, Konya Training and Research Hospital, Konya, Turkey

Correspondence Address:
Baris Sevinç
Department of General Surgery, Usak University Medical School, Usak
Turkey

Aim: Although there are several auxiliary laboratory tests, diagnosis of acute appendicitis (AA) mainly depends on clinical findings. The aim of this study was to evaluate the role of ischemia-modified albumin (IMA) in the diagnosis of AA. Methods: IMA levels of histopathologically confirmed AA cases and healthy volunteers were evaluated. Results: Mean IMA levels were 9.6 ± 12.5 absorbance units (ABSU) in the AA group and 3.04 ± 0.47 ABSU in the control group. Moreover, IMA levels positively correlated with the diagnosis of AA (r = 0.309, P = 0.013). The preoperative mean IMA level was 9.6 ± 12.5 ABSU, while the postoperative mean IMA level was 6.9 ± 11.7 ABSU (P = 0.001). There was a significant decrease in IMA levels after appendectomy. Conclusion: This study shows elevated IMA levels in patients with AA and a significant decrease of IMA levels after appendectomy. Oxidative stress plays a role in the pathogenesis of AA, and IMA levels can be used as an accessory parameter in diagnosis.


How to cite this article:
Turan E, Sevinç B, Kurku H, Simsek G, Demirgül R, Karahan &. The role of ischemia-modified albumin levels in the diagnosis of acute appendicitis.Transl Surg 2017;2:62-65


How to cite this URL:
Turan E, Sevinç B, Kurku H, Simsek G, Demirgül R, Karahan &. The role of ischemia-modified albumin levels in the diagnosis of acute appendicitis. Transl Surg [serial online] 2017 [cited 2021 Sep 26 ];2:62-65
Available from: http://www.translsurg.com/article.asp?issn=2468-5585;year=2017;volume=2;issue=3;spage=62;epage=65;aulast=Turan;type=0