| REVIEW ARTICLE |
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| Year : 2019 | Volume
: 4
| Issue : 2 | Page : 22-26 |
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Factors regulating the change of vascular smooth muscle cells in cardiovascular diseases: A mini review
Haocheng Li1, Qingfeng Sun1, Ye Yao2, Chao Yuan1, Gaoyan Liu1, Bao Jing1, Jingbo Li1, Haiyang Wang1
1 Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
2 Department of Cardiac Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Correspondence Address:
Haiyang Wang
Department of Vascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001
China
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ts.ts_4_19
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Vascular smooth muscle cells (VSMCs) are responsible for blood vessel relaxation contraction and hemodynamics. Cardiovascular diseases (CVDs) are a major cause of human death worldwide, and the pathophysiological changes to the VSMCs such as apoptosis, hypertrophy, and migration contribute to these diseases. Herein, we recapitulated the importance of molecular factors relevant to the regulation of VSMCs and how VSMCs are involved in these pathophysiological changes. This is significant to the development of therapeutic treatments for various CVDs. A literature search was conducted to identify studies assessing the regulating factors of VSMCs using the Medline and PubMed databases from inception to February 1, 2019. Search terms were applied either as single or in combination. In the present review, we will discuss some of the influential factors that may affect and regulate the changes of VSMCs in CVDs.
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