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Year : 2018  |  Volume : 3  |  Issue : 4  |  Page : 83-87

Progress of diagnosis and surgical treatment in children with moyamoya disease

1 Department of Neurosurgery, Zhujiang Hospital; The National Key Clinic Specialty, The Engineering Technology Research Center of Education Ministry of China, The Neurosurgery Institute of Guangdong Province, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Southern Medical University, Guangzhou, Guangdong, China
2 Department of Graduate School, Chengde Medical University, Chengde, Hebei, China
3 Department of Pediatrics, Chengde Central Hospital, The Second Clinical College of Chengde Medical College, Chengde, Hebei, China

Correspondence Address:
Prof. Shizhong Zhang
No. 253, Middle Industrial Road, Guangzhou 510280, Guangdong
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ts.ts_17_18

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Moyamoya disease (MMD), also known as abnormal intracranial vascular network, is a group of chronic progressive stenosis or occlusion of bilateral main branches of Willis ring (siphon segment of internal carotid artery and anterior and middle cerebral arteries, sometimes including the origin of posterior cerebral artery), followed by abnormal collateral small vascular network. The disease is known as MMD because it presents many dense piles of small blood vessels that appear as “puff of smoke” on cerebral angiogram. At present, great progress has been made in the field of epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of adult MMD. However, the disease characteristics considerably differ in children. Therefore, this article will review the diagnosis, treatment, and prognosis of MMD in children.

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